Supercharge Your Mitochondria: High Dose NAD+ No Needles: ION LAYER Brings It Home

March 18, 2023

All of the benefits of high dose prescription strength NAD+ IVs without the needles, all at home, whenever you want, for a fraction of the cost. And I absolutely love it. I feel energized but not jittery, hyper or caffeinated. I feel focused, centered and embodied. The word is – I LOVE THIS SO MUCH!

Here is the full deal on this!

Ion Laye’rs iontophoresis transdermal patches provide a non-invasive process to replenish and increase the bioavailability of NAD+ in your body. Apply your IonLayer patch like a bandaid and go about normal day-to-day activities while getting a steady drip of NAD+. After 4 hours, toss it and you’re done!

IonLayer Patch > IVs > Supplements

 

What Is Ionotophoresis?

Iontophoresis, pronounced eye-ohn-toe-for-e-sus, is usually administered with large machines, cables, and enormous localized patches that use a low electric current to deliver medication through the skin, hair follicles, and sebaceous glands (small glands that keep your skin moisturized) and into the underlying tissue.

The molecule you want to deliver is applied to an electrode pad with a similar charge and saline is placed on the opposite pad. Once the patch is applied to the skin, the electric circuit is complete and the compound begins to make its way through the skin.

For anyone that actually paid attention in physics class, this is where the principle of “like repels like” kicks in and repels the drug away from the similarly charged electrode pad and into the skin. Remember trying to push two magnets together at their similarly charged poles? That is exactly what is happening here.

While the technology of iontophoresis has existed for a long period of time, new innovations have led to single use patches that have a small battery that drives the electric charge compared to an enormous, antiquated machine that powers the patch.

Some of the unique benefits of Iontophoresis? Well, by delivering compounds using this very low current over a long time duration, this process allows more of the compound to actually penetrate the skin. Delivery through iontophoresis also generally reduces the symptoms that would arise from an enormous bolus dose injected directly into a blood vessel, which is how a lot of compounds are delivered today.

This leads to effective treatment with a very low incidence of side effects and most importantly—no needles!‍

So What Does The Science Say?

Studies like this one and this one have demonstrated the efficacy of iontophoresis delivery for compounds like vitamin C and dexamethasone, a corticosteroid commonly used to treat inflammation.

This other more specific study looked at the delivery of a compound using a iontophoresis patch and concluded that not only was the treatment well tolerated, but it also allowed for the delivery of “therapeutic drug levels for longer periods than currently possible.” This is important since delivering a compound over a long period of time is a key piece in mitigating uncomfortable side effects.

So if you like schlepping it all the way to your nearest clinic, wasting time in a waiting room, and then getting pricked by a needle to get your treatment, then maybe Iontophoresis isn’t for you.

But if you want to be able to get medication delivered through a painless patch that allows you to go about your day while getting treatment… well, then this might be the solution you’ve been waiting for.

Enter ION LAYER. 

Why Is Everyone Taking High Dose NAD+?

The world’s top physicians, biohackers, celebrities, and athletes are turning to high dose NAD+ infusions, but why?

NAD+ is a critical coenzyme your body uses to produce energy & regulate key bodily functions. The problem is that as we age the level of NAD+ in our bodies decreases which is associated with the acceleration of your body’s aging and most disease processes.

The good news? You can increase it.

INCREASING NAD+ LEVELS HAS BEEN LINKED WITH[*] THE FOLLOWING BENEFITS:

⚡️
Boosted Energy & Metabolism

NAD+ has been shown to increase your mitochondria function and ATP production, the “power plant” and energy currency of your cells that drive your energy and metabolism.[*]

📉
Reduced Inflammation

Raising NAD+ status for only one week has shown reduced expression of inflammation markers such as TNFa and IL-6 and has been shown to reduce symptoms of inflammatory autoimmune conditions.[**]

🧠
A Better Working Brain

NAD+ pathways have been shown as critical to prevent neuronal degradation, increase neuroplasticity, and counteract processes that lead to cognitive decline seen in Alzheimer’s and Parkinson’s.[*]

💪
Improved Performance & Recovery

Increasing NAD+ levels in mice has been shown to increase endurance, capacity, stem cells, and regeneration of skeletal muscle tissue.[*]

👵
Improved Longevity

NAD+ levels decline as you age. This decline is linked to age-related diseases like cognitive decline, cancer, metabolic disease, and frailty. Many of these processes have been shown to slow or even reverse by restoring NAD+ levels.[*]

🧬
Better DNA Repair

DNA damage has been linked to a variety of diseases and aging. NAD+ status improvement has been shown to increase angiogenesis, DNA repair and synthesis, and liver regeneration.[**]

putting patch on

Join Ion Layer to get 6 needle-free at-home NAD+ treatments up to $150 off.

What you Get:
1 complete kit per order
6 RX-exclusive Iontophoresis patches
3,000 mg NAD+ coverage per month (500mg/ patch)
Easy to apply

Supplements?

Some people claim that taking the supplemental precursors of NAD+ (like NMN and NR) can boost NAD+ and have a beneficial effect — I don’t buy it. There are plenty of people much smarter than I am who have debunked this and anecdotally I have taken a lot of the precursors and have felt nothing. I have tried creams, liposomal gels, pills, etc., and have noticed nothing from them.

IVs?

Getting NAD+ straight into your bloodstream seems to be the most effective way to boost levels, and that’s where we’ve noticed the most amount of benefits as well. The only way to really do that right now is via IV drips. But IV NAD+ isn’t ideal. It is super expensive ($700-1400+ per IV depending on the place and amount of NAD+!), you have to go to the clinic and sit there for hours, and because of the concentrations you get, it feels like your insides are going through a meat grinder and like you are internally vomiting. You also ideally have to go multiple days in a row, which alone is nearly impossible for most people.

IonLayer Patch > IVs > Supplements

We use iontophoresis transdermal patches that provide a non-invasive process to replenish and increase the bioavailability of NAD+ in your body. Apply your IonLayer patch like a bandaid and go about normal day-to-day activities while getting a steady drip of NAD+. After 4 hours, toss it and you’re done!

The NAD+ is delivered straight into the bloodstream, right at home, at a fraction of the cost, and with no needles. Win-win-win.

How Ion Layer Works
Mix NAD+ Solution
NAD+ is most effective when it is used immediately after it is reconstituted. This is why we offer you individually portioned vials of NAD+ and sterile water solution (blue bottles) to mix right before use.
Apply Solution to Patch
To power your Ion Layer patch, apply the provided salt solution (pink bottles) on the negative side and your NAD+ solution on the positive side. This will help push the NAD+ into your bloodstream without needles.
Apply Patch to Skin
Place your Ion Layer patch anywhere on your body that is free of hair. The included battery will begin powering the patch automatically and delivering the NAD+ to your bloodstream without any sensation.
That’s it!
Go about your day without restrictions and wear the patch for at least four hours to get a steady drip of high-dose NAD+. After fourteen hours, remove the patch just like you would a bandaid and toss.
img-vial

 

What is NAD+ and how does it really work?

NAD, or nicotinamide adenine dinucleotide, is a coenzyme that is required for over 500 biological processes (that we know of now) in the body including metabolism and energy production, cellular and DNA repair, organ function, and more.

NAD+ is the form of NAD that essentially acts like a shuttle which is able to carry electrons around the body and drop them off at certain places we need them to carry out enzymatic reactions. The more electrons available to do work, the more capacity your body has to do a whole host of things.

We naturally produce it and it’s a derivative of a B vitamin, but we produce much less of it as we age, and even less as it gets “used up” by inflammatory processes.

If you increase the amount of NAD+ it has been shown to improve energy production, reduce inflammation, extend lifespan, and impact nearly every single organ system in a positive way. You’ve probably noticed fringe health people taking NAD+ from everything from detox like us to longevity and peak health optimization and everything in between.

 

Therapeutic potential of NAD-boosting molecules: the in vivo evidence, Wajman and Sinclair, 2019
So how do you increase NAD+? The obvious ways of having a clean diet, heat/cold exposure, exercise, etc. But you can also get NAD+ exogenously (sort of similar to ketones).

That’s where IonLayer comes in. Our goal is to make high-dose NAD+ available without the needles, all at home, and for a fraction of the cost. 

If you have any questions about IonLayer or NAD+, don’t hesitate to hit reply and reach out.